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Table 5 : Cell Adhesion Molecules (CAMs)

From Gene expression in stem cell-supporting stromal cell lines. (Ann N Y Acad Sci. 2005 Jun;1044:159-67. Charbord P, Moore K)

ClassFunctionGene nameDetected in**Sequence§PW***StroCDB ID
integrin integrin subunit beta-1 ITGB1 A 4, 5, 8
integrin integrin subunit beta-5 ITGB5 A
integrin integrin subunit alpha-5 ITGA5 A, GM 8
integrin integrin subunit alpha-6 ITGA6 DB em LL6in20884
integrin CD82 antigen CD82 DB em LL6in10852T7
integrin tetraspanin 5 TM4SF9 DB em LL6in20647
integrin tetraspanin 6 TM4SF6 A, GM
integrin tumor-associated antigen L6 TM4SF1 DB em LL6in20330
integrin urokinase-plasminogen activator receptor, type 1 PLAUR DB em 6 LL6in21587
integrin related adhesion focal tyrosine kinase RAFTK/FAK2 DB em LL6in22111
integrin dedicator of cyto-kinesis 180 DOCK180 DB homol LL6in20840
integrin caveolin CAV A
integrin src homology collagen protein 66 kDa SHC A
integrin c-abl proto-oncogene tyrosine protein kinase ABL1 DB em LL6in10406T7
integrin phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, alpha isoform PIK3R1 DB em LL6in10367T7
integrin phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, delta isoform PIK3CD DB em LL6in10748T7
integrin MAPK/ERK kinase kinase 1 MEKK1/MAP3K1 DB em LL6in21767
integrin c-Jun N-terminal kinase 2 MAPK9/JNK2 DB em B72
integrin phosphoprotein enriched in astrocytes-15 kD PEA-15 A 9
integrin r-ras GTPase RRAS A
IgSF embigin EMB/GP70 A
IgSF BSG A
IgSF vascular CAM-1 VCAM1 DB em 2, 9 LL6in12032T7
IgSF Neural CAM-140 NCAM A em
IgSF Immunoglobulin Superfamily Leucine Rich ISLR DB homol 5, 9 LL6in11414T7
cadherin short type pituitary gland-brain (PB) cadherin//Gtl2 gene CDH22//GTL2 DB em LL6in22071
cadherin PCDH1 DB homol LL6in10625T7
cadherin osteoblast (OB) cadherin/cadherin 11 CDH11 DB em 8, 3 C65
cadherin polarity gene (frizzled) FZD1 DB homol LL6in12103T7
cadherin LDL-receptor related protein 6 LRP6 DB em LL6in10590T7
cadherin armadillo velo cardio facial repeat p120 catenin-like AVCFR DB em LL6in20423
cadherin APC-binding protein EB2/EB3 EB3 DB em LL6in11523T7
cadherin Transcription factor-3 TCF3 DB em LL6in20817
S-lectin galectin 3/Mac-2 LGALS3 A
S-lectin galectin 8 LGALS8 DB homol LL6in20387
S-lectin galectin 9 LGALS9 A
C-lectin mannose receptor C type 2 MRC2 A
C-lectin Ly-49F-GE antigen LY49 A
other nephroblastoma overexpressed gene NOV DB, A em LL6in20719
other dystroglycan precursor DAG1 A 8
other ectodysplasin-A EDA isoform TA A TAA DB em LL6in10029T7
other tyro10 receptor tyrosine kinase TYRO10 DB em E14
other neuroligin 2 NLGN2 DB homol LL6in22551
other sialophorin/CD43 SPN DB em LL6in10602T7
other vascular adhesion protein-1/membrane copper amine oxidase 3 VAP1/AOC3 DB em 9

** DB : StroCDB (database AFT024-2018) at http://stromalcell.princeton.edu; A : Affimetrix chips; GM : GM chips

*** PW : already given in previous works on gene product screening using stromal cells (shown in italic):

§ for gene products in the database: em = exact match; homol = homolog

1. Dieudonne SC, Kerr JM Xu T et al. Differential display of human marrow stromal cells reveals unique mRNA expression patterns in response to dexamethasone.J Cell Biochem. 1999;76 : 231-43.

2. Locklin RM, Riggs BL, Hicok KC et al. Assessment of gene regulation by bone morphogenetic protein 2 in human marrow stromal cells using gene array technology. J Bone Miner Res. 2001; 16 : 2192-204.

3. Tremain N, Korkko J, Ibberson D et al. MicroSAGE analysis of 2,353 expressed genes in a single cell-derived colony of undifferentiated human mesenchymal stem cells reveals mRNAs of multiple cell lineages. Stem Cells. 2001; 19 :408-18.

4. Jia L, Young MF, Powell J et al. Gene expression profile of human bone marrow stromal cells: high-throughput expressed sequence tag sequencing analysis. Genomics. 2002; 79 : 7-17

5. Doi M, Nagano A, Nakamura Y. Genome-wide screening by cDNA microarray of genes associated with matrix mineralization by human mesenchymal stem cells in vitro. Biochem Biophys Res Commun. 2002; 290 : 381-90

6. Graf L, Iwata M, Torok-Storb B. Gene expression profiling of the functionally distinct human bone marrow stromal cell lines HS-5 and HS-27a. Blood. 2002; 100 : 1509-11.

7. Sekiya I, Vuoristo JT, Larson BL, Prockop DJ. In vitro cartilage formation by human adult stem cells from bone marrow stroma defines the sequence of cellular and molecular events during chondrogenesis. Proc Natl Acad Sci U S A. 2002; 99 : 4397-402.

8. Wieczorek G, Steinhoff C, Schulz R et al. Gene expression profile of mouse bone marrow stromal cells determined by cDNA microarray analysis. Cell Tissue Res. 2003; 311 : 227-37.

9. Qi H, Aguiar DJ, Williams SM et al. Identification of genes responsible for osteoblast differentiation from human mesodermal progenitor cells. Proc Natl Acad Sci U S A. 2003; 100 : 3305-10.